Chapter 17 Monotonic Trend Module

This module enables users to check if the dose-response/time-course effect is monotonic or not.

17.1 Fitting Curve

This functionality showed dose-response/time-course plot with linear fitting for individual genes. It contains 3 sub-tabs.

17.1.1 Fitting Curve

The “Fitting Curve” tab shows the dose response plots.The example below shows that all 3 plots has very low R-square value, which indicate bad fit.

It is very clear that the respone keeps up and down when we change to view “Connecting Dot”.

17.1.2 Result Table and Data Table

The “Result Table” shows the fitted results in a searchable table, which are shown as labels in the plots. And the “Data Table” shows the original data of the selected genes.

17.2 Result Table (all)

This tab shows the fitted results in a searchable table for all the genes. User can apply filter condition to view the results for the filtered genes only.

17.3 Browsing

This tab allow user to view the fitting plots from previous filtered gene list.